DERMALINE

PDRN Solution Salmon Ampoule

For mature, dull, or barrier-compromised skin needing serious repair.

A clinical-grade PDRN ampoule from Dermaline — a Korean dermo-cosmetic brand that mostly sells through pharmacy and dermatology channels rather than mass retail, meaning their formulations skip the marketing flourishes and focus entirely on delivery. The hero is 10,000ppm of Sodium DNA — a high-concentration salmon-derived PDRN whose nucleotide structure is around 99.9% similar to human DNA, allowing it to be easily absorbed without triggering reactions. PDRN is the ingredient dermatologists have used in injectable form for years to support skin regeneration; this ampoule brings the same active to a topical, daily-use format.

The texture is the part that makes it daily-friendly. Lightweight, slightly viscous, fast-absorbing, with no fragrance, alcohol, or unnecessary fillers. Around the PDRN, the formula leans on niacinamide for brightening and barrier support, centella asiatica and houttuynia cordata for calming, adenosine for elasticity, and triple-weight hyaluronic acid for deep hydration. The pH sits at 5.5–6.5 to match your skin's natural acidity, and the formula is dermatologically tested for sensitive skin. Often used with derma rollers or microneedling for amplified delivery, though it works perfectly well applied alone.

Best For: Mature, dull, sagging, post-procedure, or barrier-compromised skin — also a great option for anyone wanting clinical-grade PDRN without going to a clinic, particularly post-laser, post-microneedling, or post-peel for accelerated recovery. Note: Contains salmon-derived PDRN; not suitable for those with fish allergies.

Key Ingredients
Sodium DNA (Salmon-Derived PDRN, 10,000ppm): A high-concentration salmon DNA fragment with nucleotide structure ~99.9% similar to human DNA — supports cellular regeneration, elasticity, and tissue repair. Niacinamide: Brightens, evens out tone, refines pores, and strengthens the skin barrier — pairs synergistically with PDRN for amplified anti-ageing results. Centella Asiatica & Houttuynia Cordata: A calming botanical duo that reduces redness, supports skin recovery, and reinforces the barrier — especially important when supporting PDRN's regenerative work. Adenosine: A clinically-recognised firming active that improves elasticity, supports collagen production, and helps soften the appearance of fine lines and wrinkles. Triple Hyaluronic Acid (Sodium Hyaluronate, Hyaluronic Acid + Hydrolysed HA): Three molecular weights of hyaluronic acid for layered hydration that keeps skin plump as the PDRN does its repair work.
How to Use
After cleansing and toner, attach the included applicator to the ampoule's rubber top. Invert and dispense 2–3 drops onto your fingertips or directly onto the face. Gently press and pat across your face and neck, focusing on areas showing fine lines, sagging, or dullness. Follow with serum and moisturiser. Use morning and evening for consistent results. For amplified delivery, can be used after derma roller or microneedling sessions under professional guidance. Tip: This is one of the better PDRN ampoules to layer with vitamin C — apply your vitamin C serum first on clean skin (so it gets the best absorption), then follow with the Dermaline ampoule. The two work synergistically: vitamin C brightens and protects against oxidative damage, while PDRN focuses on the deeper regeneration work. Together they deliver visible results faster than either alone.
Full Ingredients

Water, Butylene Glycol, Glycerin, Erythritol, 1,2-Hexanediol, Niacinamide, Diglycerin, Sodium DNA (10,000ppm), Methyl Gluceth-20, Centella Asiatica Extract, Panthenol, Xylitylglucoside, Polyglyceryl-10 Laurate, Betaine, Anhydroxylitol, Caesalpinia Spinosa Fruit Extract, Hydroxyacetophenone, Polyacrylate Crosspolymer-6, Caprylic/Capric Triglyceride, Xylitol, Polyglycerin-3, Kappaphycus Alvarezii Extract, Sodium Hyaluronate, Hydrogenated Lecithin, Acorus Calamus Root Extract, Adipic Acid, Perilla Ocymoides Leaf Extract, Adenosine, Glucose, Polyquaternium-51, Scutellaria Baicalensis Root Extract, Polygonum Cuspidatum Root Extract, Jasminum Officinale (Jasmine) Flower Water, Glyceryl Acrylate/Acrylic Acid Copolymer, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Glycyrrhiza Glabra (Licorice) Root Extract,Camellia Sinensis Leaf Extract, 3-0-Ethyl Ascorbic Acid, Asiaticoside, Ceramide NP, Fucus Vesiculosus Extract, Chamomilla Recutita (Matricaria) Flower Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Prunella Vulgaris Extract, Hydrolyzed Hyaluronic Acid, Dextrin, Ethylhexylglycerin, Sodium Acetylated Hyaluronate

Volume — 35 ml
PDRN Solution Salmon Ampoule
$58.00
Taxes & duties included.
Free worldwide shipping over $60. Ships from Seoul in 3–4 business days.