Genabelle

PDRN Rejuvenating Cream

For firmer, calmer, brighter skin overnight.

Genabelle's flagship cream and one of the first products to bring PDRN out of dermatology clinics and into your bathroom shelf. The headline active is 1,000ppm of medical-grade salmon-derived PDRN — small enough in molecular weight to actually penetrate the skin and trigger the regenerative response that's normally reserved for injectable treatments. Around it, Genabelle layers their patented HTD-Genacomplex™ (PDRN + three molecular weights of hyaluronic acid + tripeptide-1) and PDRS+ (extra PDRN plus four essential nucleotides: uracil, thymine, adenine, and cytosine) for amplified skin recovery.

The texture is rich without being heavy — sinks into a soft, comforting layer that locks moisture in without that occlusive, sticky feeling. Around the PDRN, the formula leans on ceramide NP for the barrier, niacinamide for brightening, acetyl hexapeptide-8 for fine line care, and centella asiatica and chamomile for soothing. Dermatest-rated "Excellent" in 2021 and suitable for sensitive, post-procedure, and reactive skin.

Best For: Mature, sensitive, dull, or post-procedure skin (think after lasers, peels, or microneedling) — also a great daily moisturizer if you want to support firmness, fade fine lines, and reinforce a stressed barrier.

Key Ingredients
PDRN (Salmon DNA, 1,000ppm) Medical-grade, low-molecular-weight DNA fragments from salmon that support skin regeneration, elasticity, and the look of healthier, calmer skin. HTD-Genacomplex The patented Genabelle blend of PDRN, three layers of hyaluronic acid, and tripeptide-1. Supports hydration, firmness, and radiance at multiple depths. PDRS+ Complex (2,010ppm) Extra PDRN plus four nucleotides (uracil, thymine, adenine, cytosine) for amplified recovery on stressed or sensitised skin. Ceramide NP Reinforces the barrier of the skin to lock in moisture and protect against environmental stress. Niacinamide and Acetyl Hexapeptide-8 A brightening-and-firming pair that evens out tone and softens the look of fine lines and wrinkles.
How to Use
As the final step of your evening routine (or both morning and evening for dehydrated skin), take a pearl-sized amount on your fingertips and gently spread across your face and neck. Pat in until fully absorbed, using upward motions to encourage circulation. Especially effective after a laser, peel, or microneedling treatment. Tip: For maximum effectiveness on stressed or post-procedure skin, layer it over a hydrating essence or serum that's still slightly damp on the skin. The cream traps that moisture beneath, helping PDRN penetrate deeper and giving you visibly bouncier skin in the morning.
Full Ingredients

Water, Dipropylene Glycol, Glycerin, Phenyl Trimethicone, Oenothera Biennis (Evening Primrose) Oil, Cetearyl Alcohol, Glyceryl Glucoside, Niacinamide, Beeswax, Arginine, PEG-100 Stearate, Hydroxyacetophenone 1,2-Hexanediol, Glyceryl Stearate, Sodium Polyacrylate, Carbomer, Dimethicone, Hydrogenated Polydecene, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Sodium DNA, Dimethicone/Vinyl Dimethicone Crosspolymer, Fragrance, Butylene Glycol, Adenosine, Trideceth-6, Disodium EDTA, Panthenol, Sodium Hyaluronate, Pentylene Glycol, Hydrolyzed Sodium DNA, Hyaluronic Acid, Tripeptide-1, Tocopherol, Uracil, Thymine, Adenine, Hydrogenated Lecithin, Portulaca Oleracea Extract, Acetyl Hexapeptide-8, Cytosine, Guanine, Centella Asiatica Extract, Chamomilla Recutita (Matricaria) Flower Extract, Vitex Agnus Castus Extract, Ceramide NP

Volume — 70 ml
PDRN Rejuvenating Cream
$35.00
Taxes & duties included.
Free worldwide shipping over $60. Ships from Seoul in 3–4 business days.